# Immunosuppressive Agents

Everolimus

Also known as Afinitor, Certican, Everolimus, RAD 001, RAD001, Votubia, Zortress A derivative of the natural macrocyclic lactone sirolimus with immunosuppressant and anti-angiogenic properties. In cells, everolimus binds to the immunophilin FK Binding Protein-12...
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Leflunomide

Also known as Arava, Leflunomida, Leflunomidum, Lefunomide, SU101 A derivative of isoxazole used for its immunosuppressive and anti-inflammatory properties. As a prodrug, leflunomide is converted to an active metabolite, A77 1726, which blocks dihydroorotate...
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Fluorouracil

Also known as 5-FU, 5-Fluoracil, 5-Fluorouracil, 5-Fluracil, AccuSite, Adrucil, Carac, FU, Fluoro Uracil, Fluorouracilo, Fluorouracilum, Fluouracil, Flurablastin, Fluracedyl, Fluracil, Fluril, Fluroblastin, Ribofluor, Ro 2-9757 An antimetabolite fluoropyrimidine...
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Fingolimod

Also known as Fingolimodum Can I take Fingolimod while breastfeeding? Because there is no published experience with fingolimod during breastfeeding, it should be avoided during breastfeeding, especially while nursing a newborn or preterm infant.[1][2][3] Drug levels...
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Sirolimus

Also known as AY 22989, RAPA, RAPAMYCIN, Rapamune, SILA 9268A, WY-090217 A natural macrocyclic lactone produced by the bacterium Streptomyces hygroscopicus, with immunosuppressant properties. In cells, sirolimus binds to the immunophilin FK Binding Protein-12...
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